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关键词： 无机及分析化学   混合式教学   兴趣教学  

摘要： 精心设计和实施了混合式教学措施,并探索了启发式、生活情景式与穿插化学史教学等行之有效的兴趣教学方式、方法,提高了学生的自主学习能力和创新能力,同时有效提升了农科无机及分析化学课程的教学效果。

关键词： 分析化学课程   绪论课   教学设计  

摘要： 分析化学课程是食品质量与安全专业的一门重要基础课程。其中,绪论课作为首次教学内容,能使学生明白该课程和后续专业课的联系以及分析方法在实践中的应用,这在激发学生的学习兴趣、提高教学效果方面具有重要的意义。基于此,在绪论课的教学设计中,可以通过应用短视频等信息化手段、分享学习和考核方法等来阐述分析化学课程与后续课程的关系,全方位、多层次地展现分析化学课程在生活、食品安全、科研中的应用,从而引起学生对分析化学课程的重视,提升他们的创新意识,达到良好的教学效果。

关键词： “互联网+”   医学检验技术专业   分析化学   教学模式  

摘要： '互联网+'时代下高职院校传统的教学模式,压抑了学生的主动性,难以适应高职院校培养具有实践能力和创新精神的应用型人才的目标。因此,本文根据职业能力标准的要求和后续课程的需要,以突出应用性和实践性为导向,合理利用各种先进的教学理念和教学手段,以互联网为平台,重点研究线上线下混合式教学模式、网络环境下PBL教学模式、'教、学、做一体化'教学模式在医学检验技术专业《分析化学》课程实践性教学中的应用,以达到提高教学质量和提高学生问题观察能力、思考能力、应用能力、操作能力等的目的。

关键词： 慕课   高校   分析化学实验   教学改革  

摘要： 慕课是云计算和大数据在教育领域的具体应用和重要体现,它的出现对传统高等教育产生深远影响。分析化学实验是分析化学课程的重要组成部分,对培养学生的科学素养、实践及创新能力具有重要作用。本文结合高校分析化学实验教学的现状,提出一些具体的教学改革措施,有效合理利用"慕课"的优势资源,将"慕课"的先进理念融合到分析化学实验教学过程中,与传统教学形成有效互补。

关键词： “翻转课堂”   分析化学   教学质量  

摘要： 将"翻转课堂"这一新型教学模式应用于高校分析化学课程教学中,结合教学案例简述了该教学模式的实施策略、实施目标及成果.研究表明,"翻转课堂"以学生为中心,充分调动了学生的学习主动性,能显著提高教师授课质量和学生学习效率.对实施"翻转课堂"模式可能存在的问题进行了剖析,对其应用价值和前景进行了阐述.以分析化学"翻转课堂"为基础和契机,与其他教学模式进行有机融合,可进一步推广至其他化学专业课程及化学基础课程的教学改革实践.

关键词： 标准化   标准滴定溶液   GB/T601—2016  

摘要： 针对标准滴定溶液的配制与标定操作中对GB/T601-2016《化学试剂标准滴定溶液的制备》较难理解,配制和标定记录未表格化、标准化,记录信息不完善,无法溯源或进行不确定度的评定等,阐述了有关内容的理解和操作,给出了EDTA标准溶液的配制和标定记录标准化的编制示例,对检验检测、化工行业的质量管理及实验人员配制标准滴定溶液记录标准化有一定的参考作用。

关键词： 分析化学   课程改革   新工科背景  

摘要： 世界范围内综合国力竞争愈加激烈,要求工程技术人才具备更高的创新创业能力和跨界整合能力,加快新工科建设,助力经济转型升级。为适应"新工科"的发展背景,化学专业应该更加强调应用性和与其他学科的关联性,注重培养复合型人才。为了提升传统理论授课的教学效果,深化教学改革,本文将从教学内容和教学模式等方面进行研究及探索。旨在提升化学相关课程的教学新颖性,提高学生的创新性和主观能动性。

关键词： CdSe nanocrystals   cation exchange   thermodynamics   isothermal titration calorimetry   nanocrystal size   capping ligands  

摘要： Among the various reported post synthetic modifications of colloidal nanocrystals, cation exchange (CE) is one of the most promising and versatile approaches for the synthesis of nanostructures that cannot be directly synthesized from their constitutive precursors. Numerous studies have reported on the qualitative analysis of these reactions, but rigorous quantitative study of the thermodynamics of CE in colloidal nanoparticles is still lacking. We demonstrate using isothermal titration calorimetry (ITC), the thermodynamics of the CE between cadmium selenide (CdSe) nanocrystals and silver in solution can be quantified. We survey the influence of CdSe nanocrystal diameter, capping ligands and temperature on the thermodynamics of the exchange reaction. Results obtained from ITC provide a detailed description of overall thermodynamic parameters equilibrium constant (K-eq), enthalpy (Delta H), entropy (Delta S) and stoichiometry (n)-of the exchange reaction. We compared the free energy change of reaction (Delta G) between CdSe and Ag+ obtained directly from ITC for both CdSe bulk and nanoparticles with values calculated from previously reported methods. While the calculated value is closer to the experimentally obtained Delta G(rxn) for bulk particles, nanocrystals show an additional Gibbs free energy stabilization of similar to-14 kJ/mol Se. We discuss a thermochemical cycle elucidating the steps involved in the overall cation exchange process. This work demonstrates the application of ITC to probe the thermochemistry of nanoscale transformations under relevant solution conditions.

关键词： Parkinson's disease   Sensor-based gait analysis   Apomorphine   Gait parameter   Precision medicine  

摘要： Mobile, sensor-based gait analysis in Parkinson's disease (PD) facilitates the objective measurement of gait parameters in cross-sectional studies. Besides becoming outcome measures for clinical studies, the application of gait parameters in personalized clinical decision support is limited. Therefore, the aim of this study was to evaluate whether the individual response of PD patients to dopaminergic treatment may be measured by sensor-based gait analysis. 13 PD patients received apomorphine every 15 min to incrementally increase the bioavailable apomorphine dose. Motor performance (UPDRS III) was assessed 10 min after each apomorphine injection. Gait parameters were obtained after each UPDRS III rating from a 2 x 10 m gait sequence, providing 41.2 +/- 9.2 strides per patient and injection. Gait parameters and UPDRS III ratings were compared cross-sectionally after apomorphine titration, and more importantly between consecutive injections for each patient individually. For the individual response, the effect size Cohen's d for gait parameter changes was calculated based on the stride variations of each gait sequence after each injection. Cross-sectionally, apomorphine improved stride speed, length, gait velocity, maximum toe clearance, and toe off angle. Between injections, the effect size for individual changes in stride speed, length, and maximum toe clearance correlated to the motor improvement in each patient. In addition, significant changes of stride length between injections were significantly associated with UPDRS III improvements. We therefore show, that sensor-based gait analysis provides objective gait parameters that support clinical assessment of individual PD patients during dopaminergic treatment. We propose clinically relevant instrumented gait parameters for treatment studies and especially clinical care.

关键词： Undergraduate laboratory course   milk powder   total protein content   moving reaction boundary titration  

摘要： Laboratory exercises focused on protein quantification are frequently conducted in traditional undergraduate biochemistry laboratory curriculum. The laboratory course described here is designed to provide students with experience in measurement of protein content in milk powder by moving reaction boundary titration (MRBT), a new rapid technique for total protein content determination in milk. In addition, this approach is weakly influenced by nonprotein nitrogen reagents such as melamine and urea. The course was done as three weekly laboratory exercises. First, students established a standard curve for milk protein concentration by MRBT method. Then, students investigated the influence of nonprotein nitrogen reagents on MRBT method. Finally, students made a comparison among three different protein quantification methods (MRBT, Biuret, and Kjeldahl method). From the experiments, students grasped the concept and advantages of MRBT and deepened the understanding of protein quantification. This course offer students the opportunity to be exposed to an advanced technique, which may have practical significance to their future study and work in the life science field. (c) 2018 International Union of Biochemistry and Molecular Biology, 46(6):644-651, 2018.