课程文献中心 更多>>

关键词： 兽医微生物学   兽医专业   兽医免疫学   甘薯黑斑病   现代兽医   《兽医微生物学》   统编教材   中共党员  

摘要： 编者按:杨本升,我国著名兽医学家,教育家,中共党员,原解放军农牧大学一级教授,专家组成员。中国现代兽医微生物学与免疫学创始人之一。他发现了我国第一例牛气肿疽病,并鉴别确认该病在我国的存在;参与确诊了我国首例牛甘薯黑斑病;在我国兽医专业中率先开设兽医免疫学课程;组织编写了我国第一部兽医微生物学高校统编教材《兽医微生物学》(兽医专业用),为中国现代兽医学教育发展作出了重要贡献。1996年因病逝于长春,享年83岁。

摘要： 222.1

摘要： 222.8

关键词： 计量范围   信息交换   数据元   一字线   交换格式   波纹线   书写规范   时间段  

摘要： 1.根据GB/T 7408-94(数据元和交换格式信息交换日期和时间表示法》,由特定起点与终点定界的时间段的表示,起点与终点之间以一字线为分隔符,而不再用波纹线。示例如下:2001—2004年,而不再表示为2001-2004年,但“~”可以用“至”取代。注意:除了上述时间段之外的其他计数、计量范围的表示,仍然用波纹线“~”表示,如:2~8 kg。

关键词： 平衡思维   医学微生物学与免疫学   教学  

摘要： 从中医学专业培养目标出发,培养学生的平衡思维是中医学专业的内在要求。平衡思维是中医类专业学生应逐步培养的思维方式,中医院校开设的医学微生物学和免疫学由于学科本身的特点,在该门课程的教学过程中加强对学生平衡思维的培养,可以促进学生平衡思维的发展和对知识的理解。本文通过若干具体案例,介绍如何在“医学微生物学与免疫学”教学中培养学生平衡思维。在传授医学微生物学与免疫学知识的同时,引导学生发现、体会、形成并逐步运用平衡思维,以便为其他学科的平衡思维培养教学提供参考。

摘要： 222.15

关键词： 微生物学与免疫学   实验教学   综合性评价  

摘要： 实验教学是高等医学教学的重要环节,建立科学合理的实验教学评价体系,对深化实验教学改革,提高实验教学质量具有重要意义。我们在微生物学与免疫学实验教学改革中,对现有的"报告式评价"模式进行了改革,初步构建了一种兼顾平时的过程评价和期末的终结评价、理论考核和实操考核的综合性评价体系,并在实践中取得了良好的教学效果。

关键词： 分子免疫学   免疫遗传学   免疫学技术   征订启事   临床免疫学   中华医学会   肿瘤免疫学   临床微生物学  

摘要： 《中华微生物学和免疫学杂志》为中华医学会主办。1981年创刊,主要报道医学微生物学和免疫学方面的研究论文、简报、评论、综述、国内外学术动态、书评及消息等。本刊辟有:细菌学、病毒学、分子微生物学、临床微生物学、疫苗学、感染免疫、基础免疫学、临床免疫学、分子免疫学、免疫遗传学、肿瘤免疫学、中药与免疫、免疫学技术、检测技术等栏目。

关键词： inflammasome   Malassezia   sebaceous glands   seborrheic dermatitis   systemic disease  

摘要： The underlying mechanism of seborrheic dermatitis (SD) is poorly understood but major scientific progress has been made in recent years related to microbiology, immunology and genetics. In light of this, the major goal of this article was to summarize the most recent articles on SD, specifically related to underlying pathophysiology. SD results from Malassezia hydrolysation of free fatty acids with activation of the immune system by the way of pattern recognition receptors, inflammasome, IL-1 beta and NF-kB. M. restricta and M. globosa are likely the most virulent subspecies, producing large quantities of irritating oleic acids, leading to IL-8 and IL-17 activation. IL-17 and IL-4 might play a big role in pathogenesis, but this needs to be further studied using novel biologics. No clear genetic predisposition has been established;however, recent studies implicated certain increased-risk human leucocyte antigen (HLA) alleles, such as A*32, DQB1*05 and DRB1*01 as well as possible associations with psoriasis and atopic dermatitis (AD) through the LCE3 gene cluster while SD, and SD-like syndromes, shares genetic mutations that appear to impair the ability of the immune system to restrict Malassezia growth, partially due to complement system dysfunction. A paucity of studies exists looking at the relationship between SD and systemic disease. In HIV, SD is thought to be secondary to a combination of immune dysregulation and disruption in skin microbiota with unhindered Malassezia proliferation. In Parkinson's disease, SD is most likely secondary to parasympathetic hyperactivity with increased sebum production as well as facial immobility which leads to sebum accumulation.

关键词： Virus   asthma   genetics   immune   microbiome  

摘要： Over the past decade, there have been substantial advances in our understanding about how viral infections regulate asthma. Important lessons have been learned from birth cohort studies examining viral infections and subsequent asthma and from understanding the relationships between host genetics and viral infections, the contributions of respiratory viral infections to patterns of immune development, the impact of environmental exposure on the severity of viral infections, and how the viral genome influences host immune responses to viral infections. Further, there has been major progress in our knowledge about how bacteria regulate host immune responses in asthma pathogenesis. In this article, we also examine the dynamics of bacterial colonization of the respiratory tract during viral upper respiratory tract infection, in addition to the relationship of the gut and respiratory microbiomes with respiratory viral infections. Finally, we focus on potential interventions that could decrease virus-induced wheezing and asthma. There are emerging therapeutic options to decrease the severity of wheezing exacerbations caused by respiratory viral infections. Primary prevention is a major goal, and a strategy toward this end is considered.