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关键词： 生物转运   主动   辅酶类/代谢   膳食   叶酸/投药和剂量   叶酸/化学   叶酸/代谢   食品   强化   高半胱氨酸/代谢   分子生物学   肿瘤/病因学   肿瘤/预防和控制   神经管缺损/病因学   神经管缺损/预防和控制   营养生理学   女(雌)性   人类   妊娠  

摘要： This paper reviews the chemistry, metabolism, and molecular biology of folic acid, with a particular emphasis on how it is, or may be, involved in many disease processes. Folic acid prevents neural tube defects like spins bifida, while its ability to lower homocysteine suggests it might have a positive influence on cardiovascular disease. A role for this B vitamin in maintaining good health may, in fact, extend beyond these clinical conditions to encompass other birth defects, several types of cancer, dementia, affective disorders, Down's syndrome, and serious conditions affecting pregnancy outcome. The effect of folate in these conditions can be explained largely within the context of folate-dependent pathways leading to methionine and nucleotide biosynthesis, and genetic variability resulting from a number of common polymorphisms of folate-dependent enzymes involved in the homocysteine remethylation cycle, Allelic variants of folate genes that have a high frequency in the population, and that may play a role in disease? formation include 677C --> T-MTHFR, 1298A --> C-MTHFR, 2756A --> G-MetSyn, and 66A --> G-MSR. Future work will probably uncover further polymorphisms of folate metabolism, and lead to a wider understanding of the interaction between this essential nutrient and the many genes which underpin its enzymatic utilization in a plethora of critical biosynthetic reactions, and which, under adverse nutritional conditions, may promote disease. (C) 2000 Academic Press.

关键词： 科技信息   兽药残留   饲用复合酶   疯牛病   生物化学与分子生物学   奶牛   科学家   腹股沟淋巴结肿大   副主任委员   微脂粒  

摘要： 1.农业部近日成立了全国兽药残留专家委员会,由陈仗榴同志任主任委员,王树槐、陈君石任副主任委员。该委员会在农业部领导下。

关键词： 生物化学   实验   分子生物学  

ISBN: (纸本)7308022803

摘要： 本书以生物高分子化合物——蛋白质、酶及核酸的分离和鉴定、代谢及其调控以及分子生物学基本实验技术为重点。

摘要： Peroxisome proliferation in rodent liver is a good biochemical marker of toxicology for several classes of xenobiotics, including fibrates: phthalates and adipates;or chlorophenoxy-acetate, a herbicide. Research in peroxisomes provides a good example of the integration of fields related to basic sciences and biomedical and industrial health. A 25 min video programme illustrates techniques involved in the characterization of purified preoxisomes and membranes, immunoblotting, measurement of proliferation markers, mRNA analysis at the post-transcriptional level, DNA techniques, cell cultures as biological models and computer analysis. It is aimed at undergraduates and non-biochemist advanced students in biology. (C) 2000 IUBMB. Published by Elsevier Science Ltd. All rights reserved.

关键词： 生物化学   分子生物学   教学内容   重新组合  

关键词： 生物化学   基础医学   分子生物学   生物化学与生物物理学报   中国科学院上海生物化学研究所   银环蛇毒素  

摘要： ~~

关键词： 生物化学   聚合度   寡糖   DNA   基础医学   碳水化合物   分子生物学   中国科学院上海生物化学研究所   生物化学与生物物理学报  

摘要： ~~

关键词： 生物化学   英语   汉语   分子生物学  

ISBN: (纸本)703005850X

摘要： 本词典收集生物化学、分子生物学及与其相关的细胞生物学、免疫学、遗传学、微生物学及医药学等方面词条约21000条，大部分词条附有简明释义。书中还收录一些缩写词和同义词。

关键词： 超表达   编码   基因   膨胀素   拟南芥   生物合成   生化反应   赤霉素   光敏色素